Study for the effect of Huatan Quyu prescription in the treatment of the patients with cerebral small vascular disease

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200055519

Enrollment

Unknown

Registered

2022-01-11

Start date

2021-01-01

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

Chinese medicine treatment group:Prescription for resolving phlegm and removing blood stasis

control group :Western medicine routine treatment

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of cerebral small vascular disease; 2. Meet the diagnostic criteria of phlegm and blood stasis syndrome of apoplexy; 3. Aged 18 to 80 years, inclusive; no gender limitation; 4. NIHSS score: 3 to 6 points, inclusive; 5. The patient is conscious; the crude determination of the force, attention and memory is basic normal; adhere to the examination and treatment; 6. The patient or legal representative agrees and signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients receiving intravenous thrombolysis; 2. Magnetic resonance angiography (MRA) showed obvious stenosis or occlusion of intracranial large vessels; 3. Unable to complete the examination, such as consciousness impairment, hearing impairment, etc.; 4. Suffering from diseases involving central nervous system, such as multiple sclerosis, carbon monoxide poisoning and other causes of white matter abnormalities; 5. Subcortical infarction or watershed infarction, subcortical infarction lesions > 20mm; 6. Hereditary small vascular disease, previous history of cerebral hemorrhage or large area of cerebral infarction, atrial fibrillation; 7. Patients with severe liver and renal insufficiency (note: Liver dysfunction refers to ALT or AST greater than 2 times the normal upper limit; Renal insufficiency (Cr > 2 times normal upper limit), hematopoietic system, tumor and other serious primary diseases and psychiatric patients; 8. MRI scan contraindications or unable to scan; 9. Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
TCM syndrome integral;National Institute of Health stroke scale, NIHSS;Barthel index;	—

Secondary

Measure	Time frame
Patient report outcome scale of stroke;	—

Countries

China

Contacts

Public ContactLiu Yanni

Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine

yanniliu0828@sina.com+86 13629189825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026