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Clinical evaluation of dietary fiber combined with Lactobacillus reuteri in the treatment of functional constipation in children

Clinical evaluation of dietary fiber combined with Lactobacillus reuteri in the treatment of functional constipation in children

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055485
Enrollment
Unknown
Registered
2022-01-10
Start date
2022-01-10
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

functional constipation

Interventions

Group 1:Lactofructose supplement
Group 2:Lactulose + dietary fiber
Group 3:Lactulose + Lactobacillus reuteri
Group 4:Lactulose + dietary fiber + Lactobacillus reuteri

Sponsors

Children's Hospital Affiliated to Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 16 Years

Inclusion criteria

Inclusion criteria: 1. From October 2020 to September 2022, children with functional constipation who were outpatients and inpatients in the Department of Gastroenterology, Children's Hospital Affiliated to Nanjing Medical University; 2. Children aged from 1 month to 16 years; 3. Requires informed consent of all children and/or parents.

Exclusion criteria

Exclusion criteria: 1. History of using any kind of laxative drug, mental retardation, metabolic disease, functional soft magnetic urinary incontinence and gastrointestinal surgery within 4 weeks before the test; 2. Those who did not complete the treatment as planned and quit halfway.

Design outcomes

Primary

MeasureTime frame
Colon transmission time;Anal rectal pressure measurement;Air bag discharge test;Colon pressure measurement;The Bristol Fecal Form Scale;Intestinal diary survey;Intestinal flora;

Countries

China

Contacts

Public ContactYang Hui

Children's Hospital Affiliated to Nanjing Medical University

xinghui7325@sina.com+86 18951769765

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026