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Efficacy and safety of 0.01% atropine eye drops for the prevention and control of myopia in children with preclinical myopia

Efficacy and safety of 0.01% atropine eye drops for the prevention and control of myopia in children with preclinical myopia

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055482
Enrollment
Unknown
Registered
2022-01-10
Start date
2022-01-10
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

Intervention group:Atropine 0.01%, both eyes, once a night
Control group:None

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Subjects who visited our hospital's optometry clinic and myopia prevention and control clinic; 2. School-age children aged 5-12 years ; 3. Equivalent diopter (after cycloplegia) is +0.75D>=SE>-0.50D, compliant astigmatism is less than -1.50D, contra-regular astigmatism is less than 0.75D, binocular anisometropia is less than 1.50D, the best corrected visual acuity of both eyes is not less than 0.8 (decimal recording method); 4. Agree to randomization and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Strabismus or other binocular vision abnormalities; 2. There are other abnormal eye and systemic diseases; 3. Have used other methods of controlling myopia within the last 3 months; 4. Other reasons considered unsuitable for inclusion by the research doctor.

Design outcomes

Primary

MeasureTime frame
axial length;refractive error;

Secondary

MeasureTime frame
best corrected visual acuity;pulil size;amplitude of accommodation;intraocular pressure;ocular surface;fundus tomography scan;

Countries

China

Contacts

Public ContactHe Meinan

Tianjin Medical University Eye Hospital

hmn509@tmu.edu.cn+86 13672135765

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026