None listed
Conditions
Interventions
Group 1:5cmH2O fixed PEEP
Group 2:Individualized PEEP titration guided by driving pressure
Sponsors
North Jiangsu People's Hospital
Eligibility
Sex/Gender
Male
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Subjects who signed the informed consent form; 2. Aged 65-80 years; 3. ASA classification II to III; 4. Body mass index 19-28kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Preoperative spine or thoracic deformity, difficult airway; 2. History of acute and chronic lung diseases, thoracic surgery and trauma; 3. Eye disease, eye trauma, eye tumor, optic neuritis, glaucoma; 4. History of psychiatric or neurological disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung function;Cerebral oxygen saturation;Width of optic nerve sheath;Middle cerebral artery blood flow; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical lung infection score;Lung infection marker; | — |
Countries
China
Contacts
Public ContactGe Yali
North Jiangsu People's Hospital
Outcome results
None listed