None listed
Conditions
Interventions
music group:After induction, bring noise reduction headphones and play background music circularly until the patient is awake at the end of the operation
control group:Only wear noise-cancelling headphones after induction
Sponsors
Fudan University Zhongshan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for radical nephrectomy under general anaesthesia; 2. ASA I or II physical status; 3. Age between 18 and 70 years old; 4. BMI between 18.5 and 24.9; 5. Voluntarily participate in this clinical trial and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with dysuria. 2.Pre-exiting cardiac insufficiency: left ventricular ejection fraction (LVEF) <50%. 3.Pre-exiting hepatic insufficiency: (prothrombin ratio <15%). 4.Pre-exiting renal insufficiency: (eGFR<30ml/min/1.73m2 5.Patients with history of mental illness. 6.Patients with history of psychotropic medication usage. 7.History of drug abuse. 8.Pre-operation hypnotic and sedative medication usage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adrenaline;Noradrenaline; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale score;Opioid dosage within 24 hours after operation;Intraoperative opioid dosage;Awakening room Richmond restless sedation score;Usage of other analgesics within 24 hours after operation;Intraoperative requirement of epinephrine.;TNF;IL-1beta;IL-2R;IL-6;IL-8;IL-10; | — |
Countries
China
Contacts
Public ContactXiong Wanxia
Fudan University Zhongshan Hospital
Outcome results
None listed