Acute Ischemic Stroke
Conditions
Interventions
Batroxobin group:Batroxobin in combination with Aspirin and Clopidogreldual antiplatelet
dual antiplatelets:Aspirin and Clopidogrel intake
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Acute ischemic stroke within 7 days; 2. Ages between 18 and 80 years; 3. Baseline plasma FIB > 1.7g/L.
Exclusion criteria
Exclusion criteria: 1. Platelet < 80×10^9/L; 2. Head CT or head MRI exclude hemorrhage transformation after cerebral infarction; 3. large scale cerebral infarction (infarction area over 2/3 of cerebral hemisphere); 4. Thrombolytic therapy with alteplase, reteplase and urokinase after onset; 5. patients treated with tirofiban after onset; 6. Emergency endovascular treatment after onset; 7. severe cardiac, hepatic and renal insufficiency; 8. Gastrointestinal ulcer active bleeding, hemoptysis, hemorrhoid bleeding within 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin scale;Proportion of fatal bleeding after medication; | — |
Secondary
| Measure | Time frame |
|---|---|
| The first reccurrence time of ischemic stroke after treatment;Time of all-cause death after medication;Proportion of non-fatal bleeding(including asymptomatic cerebral hemorrhage); | — |
Countries
China
Contacts
Public ContactJiangang Duan
Xuanwu Hospital, Capital Medical University
Outcome results
None listed