Cognitive dysfunction in antipsychotic-induced constipation
Conditions
Interventions
Group of psychotic patients taking antipsychotics and constipated:none
Group of psychiatric patients taking antipsychotics but not constipated:none
Sponsors
Xiamen Xianyue Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Psychotic patients taking antipsychotics and constipated: (1) Meet the diagnostic criteria of ICD-10 mental disorders; (2) Meet the Rome IV diagnostic criteria for constipation; (3) Constipation caused by taking antipsychotic drugs; (4) Aged 18-65 years, primary school or above, able to understand and answer the questionnaire; (5) Participate voluntarily and sign the informed consent. 2. Psychotic patients taking antipsychotics but not constipated: (1) Meet the diagnostic criteria of ICD-10 mental disorders; (2) Does not meet the Rome IV diagnostic criteria for constipation; (3) Taking antipsychotic drugs did not cause constipation; (4) Aged 18-65 years, primary school or above, able to understand and answer the questionnaire; (5) Participate voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Constipation caused by organic diseases: such as intestinal stenosis or obstruction caused by tumor, inflammation or other reasons; 2. Abdominal surgery within the past 3 months; 3. Significant changes in diet within the past 1 month; 4. Accompanied by major physical diseases or unable to cooperate with the completion of the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Near infrared spectroscopy detection;Event related potential;MATRICS Consensus Cognitive Test Set; | — |
Secondary
| Measure | Time frame |
|---|---|
| Constipation Scoring System; | — |
Countries
China
Contacts
Public ContactChen Jindong
Xiamen Xianyue Hospital
Outcome results
None listed