diabetes
Conditions
Interventions
Experimental group:Meal insulin dose adjustment by AI-assisted doctor
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetic subjects receiving intensive insulin therapy; 2. Aged >= 18 years; 3. Poor blood sugar control, HbA1c>=8.0%.
Exclusion criteria
Exclusion criteria: 1. The subject is currently pregnant, intends to become pregnant, or is unwilling and unable to use contraception during the study (female only); 2. Abnormal mental state; 3. Refuse to wear invasive examination equipment; 4. There are clear reasons for not wearing dynamic glucose monitoring (severe allergies, skin diseases, etc.); 5. The subject has symptoms and signs such as skin lesions, scarring, redness, infection or edema at the sensor application site that will affect the sensor application or the accuracy of the interstitial fluid glucose measurement; 6. Complicated serious diseases, including but not limited to heart disease, cerebrovascular disease, liver and kidney disease, severe diabetes-related complications; 7. The subject has an appointment for X-ray, MRI or CT examination during the study period, and the appointment cannot be changed to before the start of the study or after the end of the study; 8. Drugs that affect blood sugar such as glucocorticoids have been used within one month; 9. Any other reasons judged by the investigator that would make the subject unsuitable to participate in the research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glucose in target range time;The amount of time that glucose is in the low blood sugar range; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycated albumin level at last follow-up visit;The proportion of glucose data 10.0mmol/L;The proportion of glucose data >13.3mmol/L;The area under the curve of glucose <10.0mmol/L in the AGP map;The area under the curve of glucose <3.9mmol/L in the AGP map;Average of glucose data;Standard deviation of glucose data;The difference between the dose approved by the doctor and the dose recommended by the algorithm;The number of times that the doctor recommended the dose in the experimental group was different from that recommended by the algorithm;In the experimental group, the proportion of blood glucose in the range of 3.9mmol/L to 10.0mmol/L within 4 hours after insulin injection when there was a difference between the doctor-approved dose and the algorithm-recommended dose; | — |
Countries
China
Contacts
Public ContactLiu Wei
Peking University People's Hospital
Outcome results
None listed