Allergic purpuric nephritis in children
Conditions
Interventions
Tacrolimus group:Tacrolimus
Sponsors
Lanzhou University Second Hospital
Eligibility
Sex/Gender
All
Age
4 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Children with a clear diagnosis of allergic purpura nephritis, 24-hour urine protein quantitative >= 0.75g; 2. The pathological ISKDC grades are grade II, grade III and above pathological types; 3. Children aged 4-18 years.
Exclusion criteria
Exclusion criteria: 1. Patients of primary IgA nephropathy, primary nephrotic syndrome, lupus nephritis, hepatitis B virus-related nephritis, and post-streptococcal glomerulonephritis; 2. Patients with HSPN combined with organic heart disease or central nervous system disease, patients with essential hypertension, patients with vision and visual abnormalities, patients with diabetes, patients with tuberculosis and EB virus infection and other infectious diseases; 3. Those with known contraindications or allergies to the drugs used; 4. Those with poor compliance; 5. Those with drug malabsorption.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hematuria; | — |
Secondary
| Measure | Time frame |
|---|---|
| proteinuria;demographic data; | — |
Countries
China
Contacts
Public ContactYang Yonghong
Outcome results
None listed