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Relationship between uric acid stone patients and intestinal and oral flora imbalance: retrospective case analysis

Relationship between uric acid stone patients and intestinal and oral flora imbalance: retrospective case analysis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200055316
Enrollment
Unknown
Registered
2022-01-06
Start date
2022-02-01
Completion date
Unknown
Last updated
2023-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urolithiasis

Interventions

Control group:None
Uric acid stone group:None
Calcium stone group:None

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Male urinary calculi patients who have undergone surgical removal of calculi; 2. The result of stone composition analysis is uric acid; 3. Aged between 18 and 75 years; 4. Serum uric acid in men and women in high uric acid group was >420µmol/L and >360µmol/L, respectively.

Exclusion criteria

Exclusion criteria: 1. Patients with common diseases associated with calcium-containing stones (eg, primary hyperparathyroidism, primary hyperoxaluria, bowel resection, inflammatory bowel disease, renal tubular acidosis, sponge kidney, etc.); 2. Participants used antibiotics or immunosuppressants within three months prior to stool sampling, inflammatory bowel disease, irritable bowel syndrome, gastrointestinal infection, gastrointestinal tumor, bowel surgery, or diarrhea or constipation within one month prior to stool sampling.

Design outcomes

Primary

MeasureTime frame
Intestinal flora;

Secondary

MeasureTime frame
Short chain fatty acids;Oral flora;

Countries

China

Contacts

Public ContactShao Yi

Shanghai General Hospital

drshaoyi@163.com+86 13661633372

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026