Urolithiasis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male urinary calculi patients who have undergone surgical removal of calculi; 2. The result of stone composition analysis is uric acid; 3. Aged between 18 and 75 years; 4. Serum uric acid in men and women in high uric acid group was >420µmol/L and >360µmol/L, respectively.
Exclusion criteria
Exclusion criteria: 1. Patients with common diseases associated with calcium-containing stones (eg, primary hyperparathyroidism, primary hyperoxaluria, bowel resection, inflammatory bowel disease, renal tubular acidosis, sponge kidney, etc.); 2. Participants used antibiotics or immunosuppressants within three months prior to stool sampling, inflammatory bowel disease, irritable bowel syndrome, gastrointestinal infection, gastrointestinal tumor, bowel surgery, or diarrhea or constipation within one month prior to stool sampling.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| Short chain fatty acids;Oral flora; | — |
Countries
China
Contacts
Shanghai General Hospital