Clinical observation of butorphanol combined with palonosetron in preventing itching caused by epidural morphine analgesia in patients undergoing cesarean section

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200055313

Enrollment

Unknown

Registered

2022-01-06

Start date

2022-01-11

Completion date

Unknown

Last updated

2023-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

B+P group:continuous intravenous butorphanal+ intravenous injection of palonosetron

B group:continuous intravenous butorphanal

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: ASA grade 1-2, 37-42 weeks of gestation, cesarean section under combined spinal-epidural anesthesia.

Exclusion criteria

Exclusion criteria: 1. Contraindications of intraspinal anesthesia; 2. History of local anesthetics; 3. History of opioid abuse; 4. Current opioid therapy; 5. Pruritus due to pre-existing conditions; 6. BMI > 50kg/m^2; 7. Combined with obstetric critical factors.

Design outcomes

Primary

Measure	Time frame
degree of itching;	—

Secondary

Measure	Time frame
pain score;	—

Countries

China

Contacts

Public ContactChen Xinzhong

Obstetrics and Gynecology Hospital Affiliated to Zhejiang University School of Medicine

Chenxinz@zju.edu.cn+86 13575738058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026