severe trauma
Conditions
Interventions
case series:Nil
Sponsors
The Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 and above; 2. Patients who are confirmed to be severely traumatized (GCS110 times/min or TI>10 points) or those who are considered to be at risk of serious bleeding; 3. Those who come to the hospital within 3 hours of being injured and enter the emergency resuscitation unit.
Exclusion criteria
Exclusion criteria: 1. Previous history of abnormal coagulation disorders or long-term oral anticoagulant and antiplatelet drugs; 2. History of long-term alcoholism, malignant tumor, organ dysfunction, venous thromboembolism, etc.; 3. Those with contraindications to the use of tranexamic acid: (1) Those who are allergic to tranexamic acid; (2) Those who are using thrombin; 4. Cardiopulmonary arrest due to trauma before admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality within four weeks after injury; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of coagulation function; | — |
Countries
China
Contacts
Public ContactLiu Lijun
The Second Affiliated Hospital of Soochow University
Outcome results
None listed