low respiratory tract infectoin
Conditions
Interventions
case series:None
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years. 2. Fever/respiratory symptoms/pulmonary auscultation rales/increased or decreased white blood cells/increased inflammatory markers such as CRP + new lesions confirmed by lung imaging, suspected to be pneumonia; including CAP, HAP/VAP, pneumonia in immunodeficiency patients, etc. 3. Clinicians plan to perform bronchoscopy and bronchoalveolar lavage fluid mNGS to detect pathogens in patients due to clinical diagnosis and treatment needs. 4. The bronchoscopy physician assesses the patient's condition to tolerate bronchoalveolar lavage and obtain adequate bronchoalveolar lavage fluid. 5. The subjects voluntarily participate in this study and sign the informed consent form; if the subjects cannot participate in the informed process, their legal representative must participate in the informed consent process and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. The patient refuses to undergo second-generation and third-generation sequencing of bronchoalveolar lavage fluid. 2. Not enough qualified bronchoalveolar lavage fluid specimens were obtained as expected. 3. Those who do not meet the diagnostic criteria for pulmonary infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pathogen;resistance; | — |
Countries
China
Contacts
Public ContactYu Yunsong
Outcome results
None listed