Chronic Fatigue Syndrome
Conditions
Interventions
Group 1:Yan-Ling-Yi-Shou Decoction
Group 2:Yan-Ling-Yi-Shou Decoction+Graded Exercise Therapy
Sponsors
Affiliated Hospital of Nanjing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for fatigue syndrome; 2. Comply with the judgment standard of ''Traditional Chinese Medicine'' for deficiency of the heart and spleen; 3. Aged 18 to 65 years; 4. Checklist Individual Strength (CIS) score > 35 points; 5. Sign the informed consent; 6. Subjects agree to avoid other fatigue syndrome drugs during the trial.
Exclusion criteria
Exclusion criteria: 1. The subject's physical function is limited and cannot exercise moderately; 2. The subject is pregnant or breastfeeding; 3. Organic causes of the following diseases that may lead to chronic fatigue: malignant tumor, acute or chronic liver disease (hepatitis, cirrhosis), anemia, tuberculosis, chronic lung disease, cardiovascular disease (heart failure, hypertension), endocrine/metabolic diseases (diabetes, hyperthyroidism, hypothyroidism, severe obesity (body mass index (BMI) >=35), autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis); 4. The following psychosocial causes that may cause chronic fatigue: severe depression, anxiety neurosis, recent severe stress, schizophrenia, alcoholism or eating disorders (anorexia nervosa, bulimia nervosa); 5. The subject has taken the following medications within the first 2 weeks: antidepressants, anxiolytics, sleeping pills, or antihistamines; 6. Subject is taking currently recommended vitamin and mineral supplements; 7. Subject takes on an excessive workload (e.g., taking on multiple tasks); 8. The subject has a history of surgery within six months; 9. The subject has severe heart, lung, cerebrovascular disease, liver and kidney insufficiency (ALT and AST are 2 times higher than the upper limit of the normal value of the laboratory in this center; serum creatinine and blood urea nitrogen are higher than 1.5 times the upper limit of the normal value of the laboratory in this center), CBT treatment and clinical drug intervention cannot be used; 10. The subject's vital signs are unstable; 11. The subject's working environment changes frequently or other circumstances may easily lead to loss of follow-up; 12. The subject is participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Checklist Individual Strength; | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-Exertional Malaise; | — |
Countries
China
Contacts
Public ContactZhou Qing
Affiliated Hospital of Nanjing University of Chinese Medicine
Outcome results
None listed