None listed
Conditions
Interventions
Morning-afternoon Group:3 cycles of RIPC in the morning first, then 3 cycles of RIPC in the afternoon
Afternoon-morning Group:3 cycles of RIPC in the afternoon, then 3 cycles of RIPC in the morning
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. Physically and mentally healthy individuals; 3. The limbs are complete, symmetrical and functional; 4. Voluntarily participated and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Suffering from chronic diseases (hypertension, diabetes, coronary heart disease, COPD and various malignant tumors, etc.); 2. Have a long-term medication history or are currently taking any medication; 3. Past history of liver and kidney disease; 4. Past history of vascular disease; 5. Abnormal coagulation function; 6. History of severe hypoglycemia in the past; 7. Irregular work and rest, diet; 8. Pregnant patients or maternity; 9. Participated in other drug trials within six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kynurenic acid and its related metabolites;Hypoxia-inducible factor;Interleukin;Nitrite; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulse oxygen saturation;Tissue oxygen content;Perfusion index;MEQ rhythm scale;Heart rate;Blood pressure;Pittsburgh index;Noninvasive cardiac output parameters; | — |
Countries
China
Contacts
Public ContactHuang He
Outcome results
None listed