Postoperative cognitive dysfunction
Conditions
Interventions
Control group:blank
Sponsors
The Affiliated Hospital of Medical School,Ningbo University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65-80 years; 2. ASA classification I to III; 3. MMSE scale score > 23; 4. Voluntarily participate in the test and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Past history of mental illness, current neurological disease; 2. Refused/failed to complete the preoperative cognitive function test; 3. Communication disorder, inability to cooperate with researchers, such as language comprehension disorder, mental illness, epilepsy, history of Parkinson's disease or myasthenia gravis, etc.; 4. Patients with severe abnormal liver and kidney function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| brain derived neurophic factor;long-term potentiation;long-term depression;brain wave amplitude; | — |
Secondary
| Measure | Time frame |
|---|---|
| long intercortical inhibition;short intercortical inhibition; | — |
Countries
China
Contacts
Public ContactWu Xiang
Affiliated Hospital of Ningbo University School of Medicine
Outcome results
None listed