type 2 diabetes
Conditions
Interventions
intervention group:Initiate a hypoglycemic strategy based on drugs with cardio-renal protection (SGLT-2 inhibitors and/or GLP-1 receptor agonists)
control group:Treatment strategies following Chinese guidelines for the prevention and treatment of type 2 diabetes
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with type 2 diabetes; 2. Aged = 7%; 7. eGFR >= 45; 8. There are no acute complications of diabetes at present.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or planning to become pregnant within the next two years; 2. Breastfeeding or planning to breastfeed within the next two years; 3. Repeated spontaneous diabetic ketosis; 4. History of pancreatitis; 5. History of medullary thyroid cancer; 6. Repeated severe urinary tract infection; 7. The clinical conditions judged by other investigators to be unsuitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| difference of change of urine albumin creatinine; | — |
Secondary
| Measure | Time frame |
|---|---|
| difference of change of carotid intima-media thicknes;difference of development of renal complication;rate of atherosclerosis;difference of HbA1c decrease;difference of fasting glucose decrease;difference of lipid profile;difference of change of heart function;difference of change of renal function in patients with high glomerular filtration rate at baseline; | — |
Countries
China
Contacts
Public ContactJi Li'nong
Peking University People's Hospital
Outcome results
None listed