Cancer
Conditions
Interventions
Experimental group:Anesthesia induction of dexmedetomidine
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. ASA I-II level; 3. Elective abdominal surgery.
Exclusion criteria
Exclusion criteria: 1. Anemia, hemoglobin 30kg/m^2; 2. Sinus bradycardia (HR<50bpm) or high-grade heart block (II degree 2 or III degree), cardiac insufficiency, LVEF<50%, liver and kidney insufficiency; 3. Systemic or vital organ infection; 4. Long-term use of a-receptor blockers to lower blood pressure, long-term use of psychotropic drugs, antiepileptic drugs or analgesics; 5. Conversion to laparotomy, or intraoperative bleeding that requires blood transfusion; 6. Alcoholism; 7. Have a history of allergy to the anesthetics used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ED50 of dexmedetomidine for induction of genaral anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate during the induction period;Blood pressure during the induction period;The depth of anesthesia during anesthesia induction;Induction time; | — |
Countries
China
Contacts
Public ContactNi Cheng
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed