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A randomized placebo-controlled clinical trial of ultrasound-guided single-dose intra-articular steroid injection in symptomatic hip osteoarthritis

A randomized placebo-controlled clinical trial of ultrasound-guided single-dose intra-articular steroid injection in symptomatic hip osteoarthritis

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200055222
Enrollment
Unknown
Registered
2022-01-03
Start date
2022-01-17
Completion date
Unknown
Last updated
2023-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Osteoarthritis

Interventions

Experimental group:40 mg triamcinolone acetate (1 mL) + 4 mL lidocaine hydrochloride
Control group:1 mL normal saline (placebo) + 4 mL lidocaine hydrochloride

Sponsors

Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged over 40 years; 2. Meet the clinical diagnostic criteria of the American College of Rheumatology (ACR) for hip osteoarthritis; 3. Imaging evidence of hip osteoarthritis (KL>=2); 4. Mild to moderate hip osteoarthritis (KL=2,3); 5. Hip symptoms persist for 6 months; 6. Moderate to severe pain in the hip (NRS>=3, 0-10, 0=no pain).

Exclusion criteria

Exclusion criteria: 1. Taking oral hormones or allergic to hormones and 1% lidocaine; 2. History of ipsilateral hip or greater trochanteric bursa hormone injection within the past 3 months; 3. History of hip surgery on the affected side; 4. Current or past infection history of the affected hip; 5. History of inflammatory arthritis, osteonecrosis or Paget disease of the affected hip; 6. Arrangements for total hip replacement surgery of the affected hip in the recent 6 months; 7. Pregnant or lactating patients; 8. Are receiving anticoagulation therapy; 9. Patients who cannot complete the Chinese questionnaire.

Design outcomes

Primary

MeasureTime frame
Pain numerical score;

Secondary

MeasureTime frame
The Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index;EQ-5D Scale Score;

Countries

China

Contacts

Public ContactFeng Yong

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

fengyongxsh@gmail.com+86 13764046979

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026