None listed
Conditions
Sponsors
Affiliated Hospital of Weifang Medical College
Eligibility
Sex/Gender
Female
Age
23 Years to 43 Years
Inclusion criteria
Inclusion criteria: 1. Aged 23-43 years, gestational age is 37-42 weeks; 2. Expectant mothers undergoing cesarean section; 3. ASA score is I-II; 4. The subject weighs 65-95kg, including the boundary value; 5. Have a detailed understanding of the nature, significance, possible benefits, potential risks and discomfort of the trial before the trial, and voluntarily participate in this clinical trial, able to communicate well with investigators, and comply with the requirements of the entire study, and signed a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to general anesthesia; 2. Those who are allergic to ketamine hydrochloride, esketamine hydrochloride, propofol, opioids, tropisetron hydrochloride, and neostigmine; 3. The mother has neuropsychiatric disorders or insufficiency of heart, lung, liver and kidney functions; 4. The fetus has intrauterine distress; 5. Patients with a history of mental system diseases (schizophrenia, mania, bipolar disorder, mental disorder, etc.), history of drugs and cognitive dysfunction; 6. Those who have participated in other drug trials 3 months before enrollment; 7. Other investigators deem it unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;Blood oxygen saturation;Heart rate;Apgar score; | — |
Countries
China
Contacts
Public ContactWang Dewei
Affiliated Hospital of Weifang Medical College
Outcome results
None listed