A new method for early-stage lung cancer nanomedicine diagnosis based on trace exfoliated tumor cells in bronchoalveolar lavage fluid

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200055203

Enrollment

Unknown

Registered

2022-01-03

Start date

2017-10-01

Completion date

Unknown

Last updated

2023-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Gold Standard:The pathological diagnostic results of the resected tissue

Index test:Hematoxylin-eosin&#32

staining

&#32

immunofluorescence&#32

immunohistochemistry

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with lung lesions and need to undergo bronchoscopy, aged over 18 years.

Exclusion criteria

Exclusion criteria: 1. Patients with pulmonary infection and infectious pulmonary disease; 2. Patients without signed informed consent.

Design outcomes

Primary

Measure	Time frame
The detection positive rate of exfoliated tumor cells (ETCs) from broncho alveolar lavage fluid with the micropore array filtratration;The detection positive rate of circulating tumor cells (CTCs) from sputum with the micropore array filtratration;The detection specificity of exfoliated tumor cells (ETCs) from broncho alveolar lavage fluid with the micropore array filtration;The detection specificity of circulating tumor cells (CTCs) from sputum with the micropore array filtration;Positive rate of detection of exfoliated tumor cells in bronchoalveolar lavage fluid based on thin-layer fluid volume method;Detection specificity of exfoliated tumor cells in bronchoalveolar lavage fluid based on thin-layer fluid volume method;	—

Measure

Time frame

The detection positive rate of exfoliated tumor cells (ETCs) from broncho alveolar lavage fluid with the micropore array filtratration;The detection positive rate of circulating tumor cells (CTCs) from sputum with the micropore array filtratration;The detection specificity of exfoliated tumor cells (ETCs) from broncho alveolar lavage fluid with the micropore array filtration;The detection specificity of circulating tumor cells (CTCs) from sputum with the micropore array filtration;Positive rate of detection of exfoliated tumor cells in bronchoalveolar lavage fluid based on thin-layer fluid volume method;Detection specificity of exfoliated tumor cells in bronchoalveolar lavage fluid based on thin-layer fluid volume method;

—

Countries

China

Contacts

Public ContactWang Wei

w.wang@pku.edu.cn+86 13910407960

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026