diabetic wound
Conditions
Interventions
Control group:Placebo
Experimental group:Ginsenoside Rg1 combined with reduced glutathione
Sponsors
Department of Cell Biology, School of Basic Medicine, Southern Medical University, Guangdong Key Laboratory of Bone and Joint Degenerative Diseases
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the latest diabetes diagnostic criteria of the ADA (American Diabetes Association) Association; 2. Diabetic foot/wound patients aged 18-80 years with Wagner grade 2-4; 3. The target diabetic wound surface area is between 1 and 50cm^2; 4. At least one chronic wound with no healing trend for 2 weeks; 5. The patients or their families can understand the requirements of the trial and are willing to actively cooperate with this study.
Exclusion criteria
Exclusion criteria: 1. Pregnant patients, lactating patients or patients with recent reproductive needs; 2. Severe renal impairment (creatinine clearance <10ml/min); 3. The patient has any known intolerance or allergy, or reports an adverse reaction to one of the components of the investigational drug; 4. Patients who have undergone surgery or surgical revascularization (vascular reconstruction or angioplasty) within the past 2 months; 5. Patients who have participated in other clinical studies in the last 3 months; 6. Patients deemed unsuitable for this study by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of wound shrinkage;Wound healing time;Total effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptoms of infection;Prognosis recurrence rate within six months;Degree of satisfaction; | — |
Countries
China
Contacts
Public ContactBai Xiaochun
Department of Cell Biology, School of Basic Medicine, Southern Medical University, Guangdong Key Laboratory of Bone and Joint Degenerative Diseases
Outcome results
None listed