coronary heart disease
Conditions
Interventions
Gold Standard:FFR value and IMR value measured by pressure guide wire
Index test:DSA image
Sponsors
Beijing Anzhen Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. To be diagnosed or diagnosed with coronary heart disease, coronary angiography is required; 3. Understand the purpose of the trial, participate voluntarily, and sign the informed consent; 4. The reference lumen diameter of the stenotic segment of the coronary angiography is >=2mm; 5. Coronary angiography showed at least one stenosis of 30% to 90%.
Exclusion criteria
Exclusion criteria: 1. The target vessel has coronary artery bypass surgery in the past; 2. Myocardial infarction within 30 days before surgery; 3. NYHA cardiac function grade >= grade III; 4. Those with other severe diseases who are not suitable for clinical trials, such as severe arrhythmia or tachycardia, sick sinus syndrome, severe asthma, severe or very severe chronic obstructive pulmonary disease; 5. Serum creatinine > 150 µmol/L; 6. Allergy to iodine-containing contrast agents; 7. Pregnant patients; 8. Participating in other clinical trials and not yet out of the group; 9. The investigator determines that it is not suitable for diagnostic interventional operations or FFR testing, or is considered unsuitable for enrollment for other reasons; 10. There is myocardial bridge in the target lesion; 11. The target lesion involves the left main trunk or the opening of the right coronary within 3mm (stenosis>50%); 12. Low-quality angiography with poor contrast agent filling or inability to detect vessel boundaries due to various reasons, overlapping vessels or severe distortion of target vessels cannot fully expose the lesion location, and it is expected that the calculation cannot be performed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FFR;IMR;accuracy;positive predictive value;negative predictive value; | — |
Countries
China
Contacts
Public ContactZeng Yong
Beijing Anzhen Hospital Affiliated to Capital Medical University
Outcome results
None listed