Carboxytherapy efficacy in skin aging

Evaluation of carboxytherapy efficacy in skin aging through clinical and ultrasonographic assessments of skin, and pathological, immunohisochemical, and molecular studies of cutaneous status of collagen, elastin, and angiogenic factors

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200055185

Enrollment

Unknown

Registered

2022-01-02

Start date

2021-12-23

Completion date

Unknown

Last updated

2023-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin aging

Interventions

Case for clinical, ultrasonographic,pathological, immunohistochemical, and PCR studies:Carboxytherapy

Case for Clinical, Ultrasonographic, and Western blotting studies:Non

Control:Non

Eligibility

Sex/Gender

All

Age

40 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Ages > 40 years; 2. Both genders; 3. Presence of aging features in abdominal skin (including wrinkle, laxity, pigmentary alteration, stria distensae, etc.).

Exclusion criteria

Exclusion criteria: 1. Active skin infections at the site of biopsy; 2. Connective tissue diseases or genodermatoses; 3. Keloid tendency; 4. Any systemic disorder such as diabetes mellitus, kidney diseases, cardiac diseases, respiratory diseases, liver diseases, severe anemia, etc. 5. Medication (also including supplementary agents) within 6 weeks before the study initiation 6. Any antiaging treatment or procedure at the site of study within one year before study initiation; 7. Cigarette smoking and alcohol and drug abusing; 8. Pregnancy; 9. Breast feeding.

Design outcomes

Primary

Measure	Time frame
Effectiveness of carboxytherapy in skin aging in clinical view;Effectiveness of carboxytherapy in skin aging in pathological view;Effectiveness of carboxytherapy in skin aging in immunohistochemical view;Effectiveness of carboxytherapy in skin aging in ultrasonographic view;Effectiveness of carboxytherapy in skin aging in molecular view;	—

Countries

Iran

Contacts

Public ContactGholamreza Tavoosidana

Department of Molecular Medicine, School of Advanced Medical Technologies, Tehran University of Medical Sciences

g-tavoosi@tums.ac.ir00989928686167

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026