Stable first-degree degenerative lumbar spondylolisthesis
Conditions
Interventions
Control group:Intervertebral discectomy through transforaminal approach under the tunnel + intervertebral bone graft fusion and internal fixation (MIS-TLIF)
Experimental group:Simple laminectomy decompression under the tunnel (Minimally invasive decompression alone)
Sponsors
The Seventh Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Stable first-degree degenerative spondylolisthesis: (1) The forward sliding of the vertebral body does not exceed 1/4 of the mid-sagittal diameter of the vertebral body; (2) The sagittal displacement of the dynamic X-ray spondylolisthesis is less than 3mm and the change of the intervertebral angle is less than 11 degree; (3) Not associated with spondylolisthesis; 2. There are symptoms such as lower limb radicular pain, numbness, fatigue, intermittent claudication with or without low back pain; 3. Conservative treatment is ineffective for half a year. 4. Age greater than 18 years and less than 80 years.
Exclusion criteria
Exclusion criteria: 1. Systemic or local active infection; 2. Malignant tumor: The patient has a clear history of malignant tumor (except non-malignant melanoma), unless the patient has received effective treatment and no clinical symptoms and signs have been found for at least 5 years; 3. Patients who have received lumbar spine surgery in the past; 4. Those who are unable to accept or tolerate surgery due to major organ disease or other reasons, or ASA (American Society of Anesthesiologists) grade IV or above; 5. Patients with abnormal mental and social psychological functions; 6. Refused to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oswestery Disability Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| SF-36 Quality of Life Score;Surgery related conditions;Clinical function evaluation;Imaging evaluation;Low back muscle function evaluation; | — |
Countries
China
Contacts
Public ContactWei Fuxin
The Seventh Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed