Osteoarthritis of the knee
Conditions
Interventions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who need unilateral primary TKA surgery due to severe knee osteoarthritis; 2. Aged 18-80 years; 3. The preoperative American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) was grade I-III.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to anesthetics and sulfonamides; 2. There is moderate or higher knee joint deformity (varus and flexion) and joint stiffness; 3. Those who drink heavily or take opioids for a long time; 4. Language barriers and those who cannot complete the numerical rating scales (NRS) of pain; 5. Patients with neuropathy on the side of the operation; 6. Mental patients; 7. Those with previous peptic ulcer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first postoperative remedial analgesia;Postoperative dosage of remedial morphine hydrochloride; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale pain score;Range of knee motion;Quadriceps strength;Incidence of postoperative complications;Daily walking distance;The duration of hospital stay; | — |
Countries
China
Contacts
Public ContactKang Pengde
Outcome results
None listed