Venous thromboembolism
Conditions
Interventions
The experimental group 1:=one hour
The experimental group 2:>one=six hours
The experimental group 3:>six=twelve hours
The experimental group 4:>twelve =eighteen hours
The experimental group5:=eighteen hours
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Elective or emergency orthopedic surgery (outside the upper limb); 3. Caprine score VTE risk assessment =2 points, i.e., patients with moderate, high or extremely high risk of thrombosis; 4. Normal coagulation function, no history of vascular disease, no drug contraindications; 5. Preoperative lower limb vascular ultrasound examination without thrombosis; 6, conscious, can communicate normally, no mental disease or other organic diseases; 7. Actively cooperate to complete the study during the treatment period, and did not participate in other clinical trial observers.
Exclusion criteria
Exclusion criteria: 1. Congestive heart failure, pulmonary edema, or lower limb edema; 2, lower limb deep vein thrombosis, pulmonary embolism or thrombophlebitis; 3. Local abnormalities of lower limbs (such as dermatitis, gangrene, ulcers, cellulitis, infectious wounds, severe deformity of lower limbs, recent skin grafting surgery, etc.); 4. Severe atherosclerosis of lower limb vessels or other ischemic vascular diseases; 5. Abnormal bleeding or coagulation or other recent anticoagulation treatment; 6. Patients with abnormal venous flap function and varicose veins indicated by preoperative color ultrasound of lower limbs; 7. Severe peripheral nerve disease and material allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of venous thromboembolism; | — |
Secondary
| Measure | Time frame |
|---|---|
| Leg circumference;Routine blood;Four coagulation;D-dimer;Fibrinogen concentration;Pain score; | — |
Countries
China
Contacts
Public ContactGaoyuan
Chinese PLA General Hospital
Outcome results
None listed