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Evaluation of the efficacy and safety of neoadjuvant combined immunotherapy and chemotherapy in the treatment of potentially resectable esophageal squamous cell carcinoma

Evaluation of the efficacy and safety of neoadjuvant combined immunotherapy and chemotherapy in the treatment of potentially resectable esophageal squamous cell carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200055148
Enrollment
Unknown
Registered
2022-01-01
Start date
2022-01-01
Completion date
Unknown
Last updated
2023-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Squamous Cell Carcinoma

Interventions

case series:neoadjuvant combined immunotherapy and chemotherapy

Sponsors

The First Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
46 Years to 83 Years

Inclusion criteria

Inclusion criteria: All patients with esophageal squamous cell carcinoma who received neoadjuvant immunotherapy combined with chemotherapy in the Thoracic Surgery Department of the First Affiliated Hospital of Zhejiang University School of Medicine from May 2019 to May 2021.

Exclusion criteria

Exclusion criteria: 1. Lack of pre-treatment imaging assessment; 2. Image evaluation less than 2 times; 3. Previously received surgery or endoscopic interventional therapy for ESCC; 4. Those who have received radiotherapy or anti-tumor drug treatment in the past; 5. Suffering from active pulmonary tuberculosis; 6. Esophageal fistula occurred before treatment; 7. Patients with distant metastases.

Design outcomes

Primary

MeasureTime frame
Pathological remission rate;

Secondary

MeasureTime frame
Objective response rate;Adverse reaction rate;

Countries

China

Contacts

Public ContactZhu Linhai

The First Affiliated Hospital of Zhejiang University School of Medicine

luodimeihua@126.com+86 18757578589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026