Stroke
Conditions
Interventions
pcTBS group:pcTBS treatment once a day for 2 weeks
10 Hz r-TMS group:10 Hz repetitive transcranial magnetic stimulation treatment once a day for 2 weeks
sham group:Sham TMS stimulation
Healthy control group:pcTBS treatment once a day for 2 weeks
Sponsors
The First Affiliated Hospital of Fujian University
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with first-time, unilateral cerebral hemisphere cerebral infarction confirmed by cranial computed tomography (CT) or magnetic resonance (MRI) examination (The diagnosis conforms to the consensus of ''Key Points for the Diagnosis of Various Major Cerebrovascular Diseases in China 2019'' formulated by the Cerebrovascular Disease Group of the Neurology Branch of the Chinese Medical Association); 2. Aged 20-70 years; no gender limit; 3. The course of the disease is 14 days after the onset; patients with stable disease; 4. Central stroke pain; 5. No cognitive impairment, able to execute simple commands (Minimum Mental State Score MMSE>21); 6. Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Difficulty in communication, with aphasia or severe dysarthria; 2. Moderate to severe spasticity of each affected limb (modified Ashworth score >=2); 3. Severe visual impairment (visual acuity <0.3); 4. Traumatic brain injury or brain tumor; 5. Intracranial metal implants; 6. Serious medical diseases (pacemaker, liver and kidney insufficiency, infectious diseases, etc.); 7. The patient has a history of epilepsy or a family history of epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensory threshold determination;Pain threshold determination;Fugl-Meyer Upper Limb Motor Function Scale;Barthel Index Assessment;Functional near-infrared assessment; | — |
Countries
China
Contacts
Public ContactJia Jie
The First Affiliated Hospital of Fujian University
Outcome results
None listed