Cervical cancer
Conditions
Interventions
Seed implantation combination chemotherapy group:Seed implantation combination chemotherapy
Chemotherapy group:Chemotherapy alone
Sponsors
Xiang'an Hospital of Xiamen University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years. 2. Karnofsky score (Karnofsky, KPS) >= 70 points. 3. Pathologically diagnosed as squamous cell carcinoma. 4. There is only one recurrent lesion with a diameter of <=7cm. 5. Imaging confirmed non-central recurrence. 6. Received pelvic external beam radiotherapy in the past. 7. No obvious contraindications to radiotherapy and chemotherapy. 8. Patients and their family members understand the whole process of disease diagnosis and treatment, and voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Associated with liver, lung, brain, bone and other organs or other distant metastases. 2. Associated with mental illness, severe medical disease, bleeding tendency or local acute infection. 3. History of other malignant tumors in addition to cervical cancer within 5 years before enrollment. 4. Are pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Local regional progression-free survival;Progression-free survivall;Overall survival;Quality of life;Acute toxicities and late toxicities; | — |
Countries
China
Contacts
Public ContactLiang Yuqin
Xiang'an Hospital of Xiamen University
Outcome results
None listed