None listed
Conditions
Interventions
Ciprofol group:Intravenous bolus injection of cyclopofol 0.4 mg/kg
Propofol group:Propofol injection 2.0mg/kg
Sponsors
Yunnan Province Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-35 years; 2. American Anesthesiologist Classification (ASA) I-II; 3. Outpatient patients undergoing elective general anesthesia induced abortion; 4. Pregnancy time is 6 to 10 weeks; 5. Body mass index (BMI) 18-30kg/m^2; 6. Vital signs: respiratory rate >=10 and =95% when breathing air; systolic blood pressure (SBP) >=90mmHg and =60mmHg and =55 and <=100 beats/min; 7. Be able to understand the research process and method, and voluntarily participate in this research.
Exclusion criteria
Exclusion criteria: 1. Those with contraindications to intravenous general anesthesia or those who have had a history of anesthesia accident in the past; 2. Known or suspected to be allergic or contraindicated to propofol injection, cyclopofol injection and other excipients; 3. Combined with craniocerebral loss, intracranial hypertension, stroke, unstable angina, myocardial infarction; 4. Respiratory insufficiency, obstructive pulmonary disease, difficult airway or judged to be difficult for endotracheal intubation (modified Markov score grade III or IV); 5. Uncontrolled diabetes or high blood pressure; 6. Severe liver dysfunction or severe renal insufficiency; 7. History of alcoholism or drug dependence; 8. Abuse or long-term use of narcotic, sedative, and analgesic drugs; 9. Those who have a history of mental illness in the past; 10. Those who have participated in any drug clinical trials within 1 month before screening; 11. Subjects who are considered by the investigator to have any other factors that are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of anesthesia induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effects on respiratory and circulatory systems;Time of anesthesia induction;Recovery time after anesthesia;Time required to leave the hospital after anesthesia;Frequency and dose of ciprofol and propofol injection; | — |
Countries
China
Contacts
Public ContactCheng Shangchao
Yunnan Province Maternal and Child Health Care Hospital
Outcome results
None listed