Helicobacter pylori
Conditions
Interventions
Sponsors
Changzhou Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years, no gender limit; 2. No antibiotics, bismuth agents, H2 receptor antagonists, or PPIs have been used in the past four weeks; 3. 13C urea breath test is positive; 4. Agree to undergo gastroscopy to take gastric mucosal biopsy tissue samples for HP culture; 5. Agree to the initial treatment of HP eradication treatment, and be willing to cooperate with the doctor to conduct follow-up investigation of the eradication effect.
Exclusion criteria
Exclusion criteria: 1. Severe heart, liver and kidney damage; 2. Pregnant or lactating patients; 3. Previous history of upper gastrointestinal surgery, gastric cancer or pyloric stenosis; 4. Participated in other drug studies within 3 months before using the study drug; 5. Patients cannot express their main complaints correctly, such as mental illness, severe neurosis; 6. Patients with contraindications to gastric mucosal biopsy (coagulation disorders, taking anticoagulants, etc.); 7. The patient is taking non-steroidal anti-inflammatory drugs or alcoholism at the same time; 8. The patient is allergic to any of the quadruple therapy for HP eradication (Nexium, clarithromycin, amoxicillin, bismuth).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| compliance;adverse reactions; | — |
Countries
China
Contacts
Public ContactWang Xiaoyong
Changzhou Second People's Hospital
Outcome results
None listed