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Prospective, randomized controlled clinical trial study of urethral dragging anastomosis in laparoscopic radical cystectomy and ileal neobladder in situ

Prospective, randomized controlled clinical trial study of urethral dragging anastomosis in laparoscopic radical cystectomy and ileal neobladder in situ

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100055084
Enrollment
Unknown
Registered
2021-12-31
Start date
2022-01-01
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bladder cancer

Interventions

Experimental group:using the neobladder-urethral drag-and-bond anastomosis technique
Control group:using the traditonal neobladder-urethral anastomosis technique

Sponsors

The Second Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients over the age of 18 who signed the informed consent; 2. Those who were diagnosed with bladder cancer by cystoscopic biopsy or TURBT pathology before surgery; 3. Patients with indications for radical cystectomy after surgical evaluation; 4. No radiotherapy, chemotherapy and immunotherapy were performed before surgery; 5. The researcher estimates that the life expectancy of the patients is >= 6 months; 6. The patient agrees not to participate in other intervention studies during the treatment period.

Exclusion criteria

Exclusion criteria: The subjects have a history of serious diseases in the cardiovascular system, respiratory system, coagulation system or mental illness, and are judged by the investigator to be unsuitable for clinical trials.

Design outcomes

Primary

MeasureTime frame
Anastomosis time for neobladder-urethra;Operation time;Urinary diversion time;Catheter removal time;Removal time of pelvic drainage tube;The restoration time of bowel functions;Postoperative stay;Maximum postoperative urinary flow rate;Postoperative residual urine volume;Incidence of anastomotic stenosis;Incidence of anastomotic leakage;

Secondary

MeasureTime frame
Postoperative hemoglobin concentration;Intraoperative blood loss;Incidence of perioperative intestinal fistula;Incidence of perioperative infection;Incidence of perioperative intestinal obstruction;Incidence of uracratia;

Countries

China

Contacts

Public ContactZeng Tao

The Second Affiliated Hospital of Nanchang University

Taozeng40709@sina.com+86 13607919171

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026