endometrial and other intrauterine diseases
Conditions
Interventions
Control group 1:propofol+alfentanil
Control group 2:remazolam+alfentanil
Experimental group:remazolam+low-dose propofol+alfentanil
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-55 years, female; 2. Accept painless hysteroscopy diagnosis and treatment; 3. ASA classification is I or II; 4. BMI 18-28kg/m^2; 5. Voluntarily participate in this study and sign the written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe liver and kidney insufficiency; 2. Patients with central nervous system diseases; mental system diseases (schizophrenia, mania, insanity, etc.) and long-term use of sedatives or pain relievers; 3. Patients with a history of craniocerebral injury and/or cerebrovascular accident; those with possible intracranial hypertension and cerebral aneurysm; 4. Heart failure (NYHA class III-IV); unstable angina pectoris; myocardial infarction within 6 months before screening; resting ECG heart rate =450ms, female >=470ms; 5. Those who are allergic to or contraindicated to benzodiazepines, opioids, propofol, flumazenil, naloxone and other drugs and their components; 6. Patients who are judged to have difficulty in airway management: modified Markov score grade III and above; 7. Other conditions judged by the investigator to be unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulse oximetry; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bispectral index;Surgical pleth index;Injection pain;Body movement response;Time to wake up; | — |
Countries
China
Contacts
Public ContactLiao Qin
The Third Xiangya Hospital of Central South University
Outcome results
None listed