Colorectal precancerous lesions and early colorectal cancer
Conditions
Interventions
lidocaine group:Patients received an intravenous bolus injection of lidocaine 1.5 mg/kg over 10 min before induction of anesthesia, followed by a continuous infusion of 2 mg/kg/h until the end of the
control group:Patients received a perioperative 0.9% saline infusion at the same rate as the lidocaine infusion.
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing endoscopic colorectal mucosal dissection; 2. Aged >= 18 years; 3. American Society of Anesthesiologists (ASA) class 1 to 3.
Exclusion criteria
Exclusion criteria: 1. The patient refuses to participate; 2. BMI greater than 30; 3. Allergic or contraindication to study drugs; 4. History of chronic pain and long-term use of analgesic medication; 5. Severe arrhythmia; 6. Hepatic and renal dysfunction; 7. Any other conditions precluded study inclusion, such as cognitive impairment, pregnancy, or inability to communicate in Mandarin Chinese.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative cognitive recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| discharge time;propofol consumption;Incidence of overall recovery;patient's satisfiction;procedure time;the emergence time;Endoscopitst satisfaction; | — |
Countries
China
Contacts
Public ContactHao Li
Fujian Provincial Hospital
Outcome results
None listed