None listed
Conditions
Interventions
Group 1:cyclopofol injection
Group 2:propofol
Sponsors
The First Affiliated Hospital of Chengdu Medical College
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65-80 years, gender is not limited; 2. American Anesthesiologist Classification (ASA) I-III; 3. Elderly patients undergoing painless gastroscopy and/or colonoscopy in outpatient clinics; 4. Diagnosis and treatment time=10 and =95% when breathing air; systolic blood pressure (SBP) >=90mmHg and =60mmHg and =55 and <=100 beats/min; 7. Be able to understand the research process and method, and voluntarily participate in this research.
Exclusion criteria
Exclusion criteria: 1. Those with contraindications to general anesthesia or those who have had a history of anesthesia accident in the past; 2. There is sleep disorder before the examination, PSQI<=5; 3. Alzheimer's disease or cognitive impairment; 4. Known or suspected allergies or contraindications to propofol injection, cyclopofol injection excipients, opioids, etc.; 5. Subjects with acute upper respiratory tract infection, asthma attack or acute severe laryngeal disease; 6. There is a history of gastrointestinal disease: gastrointestinal retention, active bleeding, which may lead to reflux and aspiration; 7. Combined with craniocerebral injury, intracranial hypertension, stroke, unstable angina, myocardial infarction, heart failure; uncontrolled diabetes or hypertension; severe liver dysfunction or severe renal insufficiency; 8. Respiratory insufficiency, obstructive pulmonary disease, difficult airway or judged to be difficult for endotracheal intubation (modified Markov score is grade III or grade IV); 9. History of alcoholism or drug dependence; 10. Abuse or long-term use of narcotic, sedative and analgesic drugs; 11. Those who have a history of mental illness in the past; 12. Those who have participated in any drug clinical trials within 1 month before screening; 13. Subjects who are considered by the investigator to have any other factors that are not suitable for participating in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anterior retrospective memory questionnaire; | — |
Countries
China
Contacts
Public ContactYang Pingliang
Outcome results
None listed