Skip to content

Effects of tramadol combined with lidocaine on the pain of propofol injection and postoperative analgesia in patients with thoracoscopic lobectomy

Effects of tramadol combined with lidocaine on the pain of propofol injection and postoperative analgesia in patients with thoracoscopic lobectomy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100055025
Enrollment
Unknown
Registered
2021-12-30
Start date
2021-12-26
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Lidocaine group:Lidocaine was injected intravenously at 1mg/kg, and propofol was injected intravenously at 0.5mg/kg 10 minutes later
Tramadol and lidocaine group:Intravenous injection of tramadol 2mg/kg and lidocaine 1mg/kg, and intravenous propofol 0.5mg/kg 10 minutes later

Sponsors

The Second Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. ASA?-? intravenous inhalation combined general anesthesia patients, aged 40-70 years; 2. All patients underwent local infiltration of 0.5% ropivacaine and patient-controlled intravenous analgesia (PCIA) after operation.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of allergy to local anesthetics and tramadol; 2. Patients who are allergic to soybeans, peanuts or propofol, patients with severe liver and kidney diseases, and patients with gastrointestinal diseases; 3. Patients with mental illness and depression; 4. Patients with epilepsy who cannot be adequately controlled by treatment; 5. Patients with a history of chronic pain and long-term use of analgesics; 6. Aspen syndrome, pre-excitation syndrome, severe heart block patients.

Design outcomes

Primary

MeasureTime frame
pain score;

Secondary

MeasureTime frame
haemodynamics;resuscitation agitation score;incidence of perioperative nausea and vomiting;influence of postoperative analgesia;

Countries

China

Contacts

Public ContactTan Jing

The Second Affiliated Hospital of Harbin Medical University

tantanstrong@163.com+86 13836126528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026