Chiari malformation type I
Conditions
Interventions
Experimental group:According to the results of PC-MRI, individualized surgery was used
Sponsors
Sanbo Brain Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Healthy volunteers: (1) Aged 18-60 years; (2) All weights are within the normal range (18.5<BMI<23.9); (3) No history of neurological disease, no history of cervical spine, no history of head and neck surgery trauma. 2. Chiari type I patients: (1) Aged 1-75 years; (2) Medical history, physical examination and imaging examinations suggest type I cerebellar subtonsillar herniation; (3) Appropriate and agreed to undergo surgical treatment.
Exclusion criteria
Exclusion criteria: 1. The diagnosis of cerebellar tonsillar herniation is not consistent with the clinical evaluation; 2. Pregnant patients, lactating patients and children; 3. Patients with allergic constitution, low blood pressure, severe heart, lung, liver and kidney insufficiency combined with serious life-threatening primary diseases such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system cannot be treated by surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebrospinal fluid flow in craniocervical junction; | — |
Countries
China
Contacts
Public ContactFan Tao
Sanbo Brain Hospital Capital Medical University
Outcome results
None listed