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A single-center retrospective study on the predictive ability of circulating tumor cell Fth1 expression on neoadjuvant therapy response and prognosis in patients with early breast cancer

A single-center retrospective study on the predictive ability of circulating tumor cell Fth1 expression on neoadjuvant therapy response and prognosis in patients with early breast cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100054970
Enrollment
Unknown
Registered
2021-12-29
Start date
2019-08-01
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

case series:none

Sponsors

Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged =55%; 7. AST and ALT =3.0x10^9/L, neutrophil count>=1.5x10^9/L; platelet count>=100x10^9/L; hemoglobin>=90 g/L .

Exclusion criteria

Exclusion criteria: 1. History of other malignant tumors other than breast cancer in the past 5 years; 2. Metastatic breast cancer is suggested by imaging or pathology; 3. Uncontrollable pleural effusion, pericardial effusion, ascites; 4. Those with severe heart disease or discomfort who are expected to be unable to tolerate chemotherapy, including but not limited to: (1) Fatal arrhythmia or higher grade atrioventricular block; (2) Clinically significant heart valve disease; (3) ECG showing transmural myocardial infarction; (4) Uncontrolled high blood pressure; 5. The investigator believes that the patient has any other conditions that are not suitable for participating in the study.

Design outcomes

Primary

MeasureTime frame
Pathological complete response rate;Number of different types of circulating tumor cells;Expression of FTH1 in different types of circulating tumor cells;

Countries

China

Contacts

Public ContactGong Chang
changgong282@163.com+86 13925099353

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026