None listed
Conditions
Interventions
experimental group:quitting smoking
control group:none
intervention group:using varenicyl tartrate
Sponsors
The First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
Male
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Males aged 25-40 years; 2. Smoking index > 200; 3. Nicotine dependence self-rating scale score >= 5 points; 4. Right-handed; 5. Approved by the ethics committee of the hospital, all the selected patients filled out the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe respiratory, cardiovascular, and digestive system organic diseases; 2. History of central nervous system disease; 3. History of use of central nervous system-related drugs; 4. Family genetic diseases (such as history of diabetes, history of hypertension); 5. History of underlying mental illness; 6. Trauma history; 7. History of taking psychotropic drugs; 8. Recent history of anesthesia; 9. History of head trauma; 10. History of alcohol or drug abuse; 11. Those who are contraindicated in magnetic resonance examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| transcriptomics;epigenetics;metabolome of urine and blood;pharyngeal microecology;resting-state functional magnetic resonance imaging(rs-fMRI); | — |
Countries
China
Contacts
Public ContactZhang Jianqing
The First Affiliated Hospital of Kunming Medical University
Outcome results
None listed