Pelvic organ prolapse
Conditions
Interventions
case series:None
Sponsors
Chinese Academy of Medical Sciences Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Peking Union Medical College Hospital Outpatient Department of Obstetrics and Gynecology for pelvic organ prolapse patients who are going to undergo transvaginal pelvic mesh implantation for treatment of ''Uterine prolapse/fornix or anterior vaginal wall prolapse III-IV and I-II degree of posterior vaginal wall bulge''.
Exclusion criteria
Exclusion criteria: 1. Have sex or vaginal douching in the past 5 days; 2. Application of oral or vaginal antibiotics, antifungals, immunosuppressants, hormone drugs or probiotics in the past 30 days; 3. Combination of immunosuppressive diseases, breast cancer, endometrial cancer and other complications that are contraindicated in the use of vaginal estrogen; 4. If the patient has a uterus before surgery and does not undergo transvaginal hysterectomy at the same time; 5. Intraoperative bladder injury or intraoperative bleeding >500ml or postoperative hematoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Host gene expression;Vaginal microbiome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Protein expression in vaginal secretions; | — |
Countries
China
Contacts
Public ContactZhu Lan
Chinese Academy of Medical Sciences Peking Union Medical College Hospital
Outcome results
None listed