Thalassemia major
Conditions
Interventions
Sponsors
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Patients with clinical and genetic confirmation of ß-TM and dependent on blood transfusion; 2. Meet IFG and/or IGT criteria according to ADA diagnostic criteria; 3. Age >= 10 and <= 18 years; 4. Male or non-pregnant women, non-breastfeeding women, and women who have no birth plan in the next three years; 5. Not participating in other clinical trials within 3 months; 6. The children and their legal guardians voluntarily participated in the study and signed the informed consent.?
Exclusion criteria
Exclusion criteria: 1. Congestive heart failure and severe pulmonary and renal dysfunction; 2. Impaired liver function, obvious clinical signs or liver disease symptoms, ALT or AST >= 3 x ULN; 3. Stress or other secondary hyperglycemia; 4. Taking drugs that affect glucose metabolism, including hypoglycemic drugs; 5. Active infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood glucose;HbA1C; | — |
Countries
China
Contacts
Public ContactLiang Liyang
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Outcome results
None listed