The Optimal Anesthesia Depth With Propofol Closed-Loop Administration in Patients Undergoing Robot-Assisted Radical Thyroidectomy via Bilateral Axillo-Breast Approach

Explore the Optimal Anesthesia Depth with Propofol Closed-Loop Administration to Effectively Inhibit Surgical Stress Response in Patients Undergoing Robot-Assisted Radical Thyroidectomy via Bilateral Axillo-Breast Approach

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054937

Enrollment

Unknown

Registered

2021-12-29

Start date

2022-01-01

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid cancer

Interventions

Group H:Anesthesia maintenance: target BIS value 55±5

Group L:Anesthesia maintenance: target BIS value 45±5

Eligibility

Sex/Gender

All

Age

16 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification:I-III; 2. Aged 16~60 years, gender is not limited; 3. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. BMI > 32 or < 16; 2. Pregnant; 3. The patient and or family members refuse or are unable to cooperate; 4. Patients with previous diseases of cardiovascular system, respiratory system, nervous system, blood system or metabolic system were excluded; 5. Patients with previous propofol allergy; 6. Previous history of mental illness.

Design outcomes

Primary

Measure	Time frame
IL-6;CRP;	—

Secondary

Measure	Time frame
Visual analogue scale;	—

Countries

China

Contacts

Public ContactGao Chengjie

Weifang Medical University

gaocj@gmail.com+86 13589108967

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026