Application of mono-, bi- and stretch exponential models diffusion weighted imaging in diagnosis and staging of liver fibrosis

Prospective clinical trial of multimodal MRI quantitative parameters in early hepatic fibrosis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100054936

Enrollment

Unknown

Registered

2021-12-29

Start date

2022-01-01

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatic fibrosis

Interventions

Gold Standard:Pathological results of liver biopsy.

Index test:Multi-parameter DWI.

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. 18-60 years old, no gender requirement; 2. Previous history of hepatitis; 3. No puncture or other pathological examination was performed in other hospitals; 4. Agree to accept the experiment.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactation patients; 2. People who are allergic to metal; 3. Patients with the following diseases: allergic disease, bleeding tendency disease, cardiovascular disease, cancer, neuropsychiatric disease and heart disease; 4. There are used drugs such as sedatives, drugs for treating depression, steroids and hormone drugs; 5. Patients with metal or other reasons that cannot be examined by MRI.

Design outcomes

Primary

Measure	Time frame
Dispersion rate;	—

Countries

China

Contacts

Public ContactLiu Tianzhu

Guangdong Hospital of Traditional Chinese Medicine (Zhuhai)

hadesfantasy012@21cn.com+86 13425022108

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026