A prospective cohort study of gut microbiota abundance in patients with cardiac arrest to evaluate neurologic outcome

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100054931

Enrollment

Unknown

Registered

2021-12-29

Start date

2022-01-31

Completion date

Unknown

Last updated

2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac arrest

Interventions

the group with good prognosis of neurological function (CPC score 1-2) vs. the group with poor prognosis of neurological function (CPC score 3-5):Nil

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged > 18 years; 2. Spontaneous circulation (ROSC) was restored after CPR in patients with CA in or out of hospital.

Exclusion criteria

Exclusion criteria: 1. The end-stage of chronic diseases such as malignant tumors and any expected survival time less than 6 months; 2. The time from cardiac arrest to ICU admission is more than 24 hours, and the data collection is incomplete; 3. Taking history of antibiotics or microbial agents within 1 month; 4. Previous history of chronic intestinal diseases.

Design outcomes

Primary

Measure	Time frame
16SrRNA gene sequence of intestinal flora;Brain function classification (CPC) score;Neuron Specific Enolase;S-100 protein beta chain;	—

Countries

China

Contacts

Public ContactDiao Mengyuan

Hangzhou First People's Hospital

zhutt65@126.com+86 13634164536

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026