A comparative study of surgical treatment of varus and valgus deformity by mechanical alignment, anatomic alignment or kinematic alignment in total knee arthroplasty

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054927

Enrollment

Unknown

Registered

2021-12-29

Start date

2022-01-01

Completion date

Unknown

Last updated

2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee

Interventions

Mechanical alignment group:Total knee arthroplasty with mechanical alignment

Kinematic alignment group:Total knee arthroplasty with kinematic alignment

Anatomic alignment group:Total knee arthroplasty with anatomic alignment

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Adults suffering from knee pain and deformity with varying degrees and a femorotibial angle FTA > 10 degrees or < 0 degrees; 2. It is the first time for them to undergo a TKA; 3. BMI <= 30kg/m^2; 4. No surgical contraindications.

Exclusion criteria

Exclusion criteria: 1. Knee tumor; 2. Valgus or varus knee led by external deformity; 3. Those with joint active infection or severe heart, lung, liver, kidney, blood and other medical diseases that cannot tolerate surgery.

Design outcomes

Primary

Measure	Time frame
Knee Society Score;Visual Analogue Scale;Oxford Knee Sessement;CT;Plain knee film;The Western Ontario and McMaster University of Orthopedic Index;Range of motion;	—

Secondary

Measure	Time frame
The length of incision;Blood loss;	—

Countries

China

Contacts

Public ContactXu Jie

Fujian Provincal Hospital

jiexud@126.com+86 13950481734

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026