Colorectal Lateral Spreading Lesions
Conditions
Interventions
Experimental group:p-CSP
Control group:ESD
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, regardless of gender; 2. Colonoscopy showed that the lesion was located in the colon and rectum; 3. The diameter of the lesion was more than 20 mm (no upper limit), and the growth mode was lateral development; 4. Be able to voluntarily sign or provide informed consent; 5. The morphology is granular or non granular; 6. If there is nodular change, the diameter of the nodule is less than 10 mm; 7. Endoscopic observation showed that the surface of the lesion was adenomatous (Kudo III/IV, JNET 2a, NICE type 1/2).
Exclusion criteria
Exclusion criteria: 1. Those who fail to stop taking aspirin, clopidogrel, prasugrel, tigrel and other antiplatelet drugs or anticoagulants such as warfarin and heparin or have coagulation dysfunction (platelet count = 1.5); 2. Patients with colorectal surgery history (excluding endoscopic lesion resection) or tumor undergoing radiotherapy and chemotherapy; 3. Pregnant or breastfeeding patients; 4. Patients with inflammatory bowel disease; 5. The lesions involved ileocecal valve, the opening of appendix or around anus; 6. Unsatisfactory bowel preparation (Boston bowel cleanliness score < 2 for the colon segment involved in the lesion); 7. Combined with colorectal cancer; 8. There were scars after previous endoscopic resection at and 10mm near the lesion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate at follow-up colonoscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Endoscopic complete resection rate;Intraoperative and postoperative complication rates; | — |
Countries
China
Contacts
Public ContactLi Quanlin
Zhongshan Hospital, Fudan University
Outcome results
None listed