Helicobacter pylori infection
Conditions
Interventions
HDDT group:HDDT
Traditional quadruple therapy group:Traditional quadruple therapy
Sponsors
Xiamen Changgung Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-45 years in the Department of Gastroenterology, Xiamen Changgung Hospital; 2. Patients with existing Hp infection or failure of previous Hp treatment who had stopped taking the drug for more than 6 months were recruited for this study; 3. Complete gastroscopy before eradicating HP.
Exclusion criteria
Exclusion criteria: 1. Taking drugs that may affect the study results (such as PPI, H2 receptor antagonist, antibiotic, bismuth within 4 weeks prior to enrollment); 2. Patients with gastrointestinal malignancy, and previous gastric and esophageal surgery; 3. Allergic to the drugs in the study; 4. Planning pregnancy, pregnancy, breastfeeding and alcohol abusers; 5. Medical conditions or clinical conditions that may interfere with the treatment evaluation of the study, such as liver disease, cardiovascular disease, lung disease, kidney disease, metabolic disease, psychiatric illness, or malignant tumor; 6. Use of adrenal corticosteroids, non-steroidal anti-inflammatory drugs and anticoagulants; 7. Patients with healing/active duodenal or gastric ulcer, gastric mucosa-associated lymphoid tissue lymphoma, atrophic gastritis, intestinal metaplasia, etc.; 8. Participate in other clinical studies within 3 months prior to participating in this clinical study; or incomplete follow-up or noncompliance with study treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori breath test; | — |
Countries
China
Contacts
Public ContactLiu Wen
Xiamen Changgung Hospital
Outcome results
None listed