The combination of lingual mucosa-small intestinal submucosa in the application of long segment of ureteral strictures treatment

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100054880

Enrollment

Unknown

Registered

2021-12-28

Start date

2021-12-27

Completion date

Unknown

Last updated

2022-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ureteral stricture

Interventions

Experimental group:Ureteral reconstruction surgery using lingual mucosa-small intestinal submucosa (SIS) combined splicing graft

Eligibility

Sex/Gender

All

Age

18 Years to 69 Years

Inclusion criteria

Inclusion criteria: 1. Sign informed consent books and label the date, understand the study, be willing to follow and able to complete all study procedures. 2. Promise to abide by the research procedures and cooperate with the implementation of the whole process of research. 3. Patients who conform to the diagnosis of benign ureteral stricture and can tolerate surgery through evaluation of each system function. 4. Patients with long strictures of the proximal or mid ureter (>2 cm) who are not suitable for direct ureteral-ureteral end-to-end anastomosis. 5. Male or female, aged >= 17 and < 70 years. 6. The subjects must have good compliance.

Exclusion criteria

Exclusion criteria: 1. Lingual mucosal graft lesions and other conditions in which lingual mucosal graft cannot be sampled (occupational patients such as broadcasters). 2. Allergy to porcine materials. 3. Patients with urinary infection or positive results of urine culture. 4. Having active tuberculosis. 5. Those who are alcohol-dependent or have a history of drug use or drug abuse in the past year, and have a clear history of mental disorders in the past. 6. Uncontrolled systemic diseases, such as diabetes and hemorrhagic diseases. 7. Pregnancy or lactation, or expected pregnancy/birth during the trial period. 8. Patients considered unsuitable for this study by the investigator for other reasons.

Design outcomes

Primary

Measure	Time frame
Urography;Endoscopy;Renal pelvis pressure;	—

Secondary

Measure	Time frame
Laboratory tests;Ultrasonography;Radionuclide renal dynamic imaging;Spiral CT urography;	—

Countries

China

Contacts

Public ContactLi Bing

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

bingli@hust.edu.cn+86 13871361899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026