Skip to content

Efficacy and safety of lidocaine plaster combined with gabapentin in the treatment of herpes zoster neuralgia: a randomized controlled clinical trial

Efficacy and safety of lidocaine plaster combined with gabapentin in the treatment of herpes zoster neuralgia: a randomized controlled clinical trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100054858
Enrollment
Unknown
Registered
2021-12-28
Start date
2021-07-01
Completion date
Unknown
Last updated
2022-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes zoster neuralgia

Interventions

Gabapentin group:Gabapentin
Lidocaine plaster group:Lidocaine plaster
Lidocaine plaster combined with gabapentin group:Lidocaine plaster combined with gabapentin

Sponsors

Nanjing Drum Tower Hospital, School of Medicine, Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of herpes zoster neuralgia; 2. Patients aged >= 18 years, male and female; 3. Had received antiviral therapy before admission, and pain control was not satisfactory, visual pain analogue scale (VAS) >= 4; 4. No neurological dysfunction; 5. Able to understand and fill in various rating scales; 6. Voluntarily sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, lung or renal insufficiency; 2. Patients with coagulation disorder; 3. Patients with cognitive dysfunction or poor coordination; 4. Allergic constitution or history of drug sensitivity with similar drug structure; 5. Patients with test drug contraindications (respiratory depression, paralytic ileus, delirium); 6. Have a history of drug abuse; 7. Patients with mental disorders or those deemed unsuitable for the study by the researcher.

Design outcomes

Primary

MeasureTime frame
VAS (Visual Analogue Scale);

Secondary

MeasureTime frame
ID Pain (neuropathic pain);SF-MPQ (Short-Form McGill Pain Questionnaire);PSQI (Pittsburgh sleep quality index);SF-36 (Short Form 36-Item Health Survey);

Countries

China

Contacts

Public ContactLin Jian

Nanjing Drum Tower Hospital, School of Medicine, Nanjing University

huangy0808@126.com+86 13951012988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026